To enable single-key shortcuts, open the Preferences dialog box, and under General, select the Use Single-Key Accelerators To Access Tools option.
| Tool | Windows/UNIX action | Mac OS action |
| Hand tool | H | H |
| Temporarily select Hand tool | Spacebar | Spacebar |
| Select tool | V | V |
| Snapshot tool | G | G |
| Marquee Zoom tool | Z | Z |
| Temporarily select Dynamic Zoom tool (when Marquee Zoom tool is selected) | Shift | Shift |
| Temporarily zoom out (when Marquee Zoom tool is selected) | Ctrl | Option |
| Temporarily select Zoom In tool | Ctrl+spacebar | Command+spacebar |
| Select Object tool | R | R |
| Object Data tool | O | O |
| Article tool | A | A |
| Crop tool | C | C |
| Link tool | L | L |
| Text Field tool | F (Windows only) | F |
| Cycle through forms tools: Text Field, Check Box, Radio Button, List Box, Combo Box, Button, Digital Signature, Barcode | Shift+F (Windows only) | Shift+F |
| 3D tool | M | M |
| Cycle through Multimedia tools: Flash, Video | Shift+M | Shift+M |
| TouchUp Text tool | T | T |
| Cycle through TouchUp tools: TouchUp Text, TouchUp Reading Order, TouchUp Object | Shift+T | Shift+T |
| Measuring tool | B | B |