Keys for general navigating on PDF File are use as follows:
| Result | Windows/UNIX Action | Mac OS Action |
| Move focus to menus (Windows, UNIX); expand first menu item (UNIX) | F10 | Control+F2 |
| Move focus to toolbar in browser and application | Shift+F8 | Shift+F8 |
| Move to next open document (when focus is on document pane) | Ctrl+F6 | Command+F6 |
| Move to previous open document (when focus is on document pane) | Ctrl+Shift+F6 | Command+Shift+F6 |
| Close current document | Ctrl+F4 | Command+F4 |
| Close all open documents | Not available | Command+Option+W |
| Move focus to next comment, link, or form field in the document pane | Tab | Tab |
| Move focus to document pane | F5 | F5 |
| Move focus to previous comment, link, or form field in the document pane | Shift+Tab | Shift+Tab |
| Activate selected tool, item (such as a movie clip or bookmark), or command | Spacebar or Enter | Spacebar or Return |
| Open context menu | Shift+F10 | Control+click |
| Close context menu | F10 | Esc |
| Return to Hand tool or Select tool | Esc | Esc |
| Move focus to next tab in a tabbed dialog box | Ctrl+Tab | Not available |
| Move to next search result and highlight it in the document | F3 | F3 |
| Search previous document (with Search results displaying multiple files) | Alt+Shift+Left Arrow (Windows only) | Command+Shift+Left Arrow |
| Search next document (with Search results displaying multiple files) | Alt+Shift+Right Arrow (Windows only) | Command+Shift+Right Arrow |
| Select text (with Select tool selected) | Shift+arrow keys | Shift+arrow keys |
| Select next word or deselect previous word (with Select tool selected) | Shift+Ctrl+Right Arrow or Left Arrow | Not available |
